Complex regional pain syndrome (CRPS)
- Article
- 2021-03-05
Complex regional pain syndrome (CRPS) is a condition characterized by severe, long-lasting chronic pain (longer than six months) that can be constant. Symptoms vary in intensity and duration. Some people describe it as a burning sensation, a pinprick sensation, or as if an arm or leg is being pinched. The pain can spread all over the arm or leg, even though the injury may have been only to a finger or toe. Common symptoms include dramatic changes in the color and temperature of the skin over the affected limb or body part, accompanied by intense burning pain, increased sensitivity in the affected area, skin tenderness, abnormal sweating, and abnormal movement in the affected limb . In most cases, the condition is caused by a clear history of trauma or injury. CRPS also affects the immune system - the condition is more common in individuals with other inflammatory and autoimmune diseases such as asthma. Limited data also suggests that CRPS may also be affected by genetics.
Therapy
There is no cure for CRPS, and no drug has been specifically approved for the condition. Treatments aim to relieve painful symptoms. Doctors can prescribe topical analgesics, antidepressants, corticosteroids, and opioids to relieve pain, but no single drug or combination of drugs has produced consistent long-term improvement in symptoms. Other treatments may include physical therapy, nerve blocks, spinal cord stimulation, and other types of neurostimulation and surgery.
Prognosis
The prognosis for CRPS varies greatly from person to person. Early treatment, especially rehabilitation, can help limit the condition. Younger people, children, and teens generally have better results. Some older adults have good results, while others continue to experience severe pain despite treatment.
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